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51.
Dr. Joaquim Torra Dr. Felipe Viela Dr. Diego Megías Dr. Begoña Sot Prof. Cristina Flors 《Chemistry (Weinheim an der Bergstrasse, Germany)》2022,28(19):e202200026
CRANAD-2 is a fluorogenic curcumin derivative used for near-infrared detection and imaging in vivo of amyloid aggregates, which are involved in neurodegenerative diseases. We explore the performance of CRANAD-2 in two super-resolution imaging techniques, namely stimulated emission depletion (STED) and single-molecule localization microscopy (SMLM), with markedly different fluorophore requirements. By conveniently adapting the concentration of CRANAD-2, which transiently binds to amyloid fibrils, we show that it performs well in both techniques, achieving a resolution in the range of 45–55 nm. Correlation of SMLM with atomic force microscopy (AFM) validates the resolution of fine features in the reconstructed super-resolved image. The good performance and versatility of CRANAD-2 provides a powerful tool for near-infrared nanoscopic imaging of amyloids in vitro and in vivo. 相似文献
52.
《Arabian Journal of Chemistry》2020,13(11):8424-8457
Nowadays, increasing extortions regarding environmental problems and energy scarcity have stuck the development and endurance of human society. The issue of inorganic and organic pollutants that exist in water from agricultural, domestic, and industrial activities has directed the development of advanced technologies to address the challenges of water scarcity efficiently. To solve this major issue, various scientists and researchers are looking for novel and effective technologies that can efficiently remove pollutants from wastewater. Nanoscale metal oxide materials have been proposed due to their distinctive size, physical and chemical properties along with promising applications. Cupric Oxide (CuO) is one of the most commonly used benchmark photocatalysts in photodegradation owing to the fact that they are cost-effective, non-toxic, and more efficient in absorption across a significant fraction of solar spectrum. In this review, we have summarized synthetic strategies of CuO fabrication, modification methods with applications for water treatment purposes. Moreover, an elaborative discussion on feasible strategies includes; binary and ternary heterojunction formation, Z-scheme based photocatalytic system, incorporation of rare earth/transition metal ions as dopants, and carbonaceous materials serving as a support system. The mechanistic insight inferring photo-induced charge separation and transfer, the functional reactive radical species involved in a photocatalytic reaction, have been successfully featured and examined. Finally, a conclusive remark regarding current studies and unresolved challenges related to CuO are put forth for future perspectives. 相似文献
53.
应用格子Boltzmann三维模型,对双气泡在静水中的运动进行数值研究.采用八点差分和十八点差分格式分别求解一阶▽φ和二阶▽2φ可以有效避免气液密度比过大造成的数值不稳定问题.结果表明:当两个相同直径的气泡在上升时,位置靠上的气泡形状变化像单气泡上升一样,而位置靠下的气泡会受到前一个气泡尾迹的影响,并有很明显的形状变化.当两个气泡直径不同时,不管初始位置如何,大气泡总会对小气泡造成强烈的影响. 相似文献
54.
Djamel Ait-Akli & Abdelkader Merakeb 《偏微分方程(英文版)》2020,33(1):64-92
In this paper we consider the Lamé system on a polygonal convex domain
with mixed boundary conditions of Dirichlet-Neumann type. An explicit L2 norm
estimate for the gradient of the solution of this problem is established. This leads to an
explicit bound of the H1 norm of this solution. Note that the obtained upper-bound is
not optimal. 相似文献
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The eigenvalues of a differential operator on a Hilbert-Pόlya space are determined. It is shown that these eigenvalues are exactly the nontrivial zeros of the Riemann $\zeta$-function. Moreover, their corresponding multiplicities are the same. 相似文献
58.
Genni Fragnelli 《复变函数与椭圆型方程》2020,65(8):1343-1359
ABSTRACTWe consider a system for a generalized Schnakenberg model, showing Turing pattern formation for a wide class of nonlinearities. 相似文献
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ABSTRACTNumerical approximations of the solution of a boundary value problem when an exact solution is not available can be constructed by means of a variety of methods. In this paper, we present a technique that is based on the integral representation of the solution of an elliptic problem and the properties of the associated layer potentials. The procedure is illustrated in application to the mathematical model of bending of plates with transverse shear deformation in a finite domain, in the presence of Dirichlet, Neumann, and Robin conditions prescribed on the boundary. 相似文献